BioReference PRELIMINARY LABORATORIES en OPKO Health Comeuny IORSHER, STUART EPSTEIN, JEFFREY DOB: 61/26/1953 Age: 64 Y Sex! M | C3076 - STUART ORSHER, M.D. wees Bed: | Patient ID: . Address:9 EAST 71ST STREET, mew YORK, NY 19022 Date Collected: 99/15/2617 08:57 Date Received: 99/15/2017 23:86 9 EAST 79TH ST, INEW YORK, NY 16621 | North America Eastern Time Notes: Non FASTING NOTE: SST tube submitted was inadequately spun. Serum was found to contain R@Cs. Certain tests, e.g. Glucose, may be decreased while others e.g. Potassium or LDH may be elevated. } NICAL REPORT Clinical Abnormalities Summary; ‘“°Y "ot contain @ piesa review oF Cholesterol 224 HI Triglycerides HDL CHOL., DIRECT 28 LO HOL as % of 13° Chol/HDL Ratio 77° NON-HDL 195 HI Cholesterol CHOLESTEROL HEP. A Ab., TOTAL Reactive * HEP. B SURF. AB, Reactive * 250H, VITAMIN D 34.5 LO PTH(3), INTACT 106.0 HI CHEMISTRY * Aloumin : . 88/30/2017 Calcium = ——— —sst—“‘i‘“—;ststs™*CSCSCSCSSCS " a a “88/36/2017 ~~ Cholesterol < | 8/38/2817 Triglycerides = = SOSOOt—C<i=~CSt “ise : ~~ “| 68/36/2077 HDL CHOL., DIRECT | 8/30/2017 HOL as % of Cholesterol === =——OS~S* “Ye8 73672817 Evaluation: ABOVE AVG. (MODERATE RISK) Chol/HDL Ratio 7.7 <7.4 | TNP 08/38/2017 Evaluation: ABOVE AVG. (MODERATE RISK) LDL /HOL Ratio ~~ : Can't Caic <3.56° , TNP 68/30/2617 [NON-HDL CHOLESTEROL 195 HI <138 mg/dl UOC Cholesterol. ee Sant Cale” <i6e “mg/L Can*t Calc ~ | e8/38/2017 NOTE; Wnable to. calculate LOL due to a Triglyceride level of greater than 400 mg/dl. VLOL, CALCULATED Can't Cale 7-32 mg/d | Can't Cate | €8/30/2617 Can't Cale: One or more components was outside the measurable range. We are unable to calculate. @.178-4.538 uTU/aL 8/30/2817 2. gg B87 38/2617 BioReference Laboratories, Inc. James Weisberger M.D. Page 1 of 4 481 Edward 1. Ross Dr | Elmood Park, x2 07407 | Laboratory Director printed @9/19/2017 11:48 EFTA00299761

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BioReference PRELIMINARY L_ABORATOR es ec OPKO Gepith Company ORSHER, STUART | EPSTEIN, JEFFREY Specimen 1D: 104659429 (DOB; 02/20/1953 Age: 64 Y Sex: M Date Of Report: 69/19/2017 05:29 | _ sTUAR U/FL: Bed: Date Collected: 69/15/2017 08:57 jese7e - STUART ORSHER, M.D. Rm: | Date Received: 99/15/2817 23:6 patient ID: Address: 2 EAST 71ST STREET, NEW YORK, NY 10822 9 EAST 79TH ST, | EW YORK, NY 10021 cct #: (C3076) --months post-infection. | --Test developed and characteristics determined by ARUP --Laboratories. See Compliance Statement A: aruplab.com/CsS ~-wai.aruplab.com, Julio Delgado, MD - Lab. Director B. quintana ab, Igé <1:64 ==INTERPRETIVE INFORMATION; Bartonella quintana Antibody, Ig6 ~« Less than 2:64 .....-. Negative: No significant level of -- Bartonella quintana IgG antibody - detected. -- 4:64 - 1:228 ....,... Equivocal: Questionable presence -- of Bartonella quintana IgG -- antibody detected. Repeat testing -- in 16-14 days may be helpful. ++ 4:256 or greater ..... Positive: Presence of IgG -- antibody to Bartonella quintana -- detected, suggestive of current ad or past infection. --A low. positive suggests past exposure or infection, while high --positive results may indicate recent or current infection, but is ~-ineonelusive. for diagnosis. Seroconversion between acute and --convalescent sera is considered strong evidence of recent --infection. The best evidence for infection is a significant change --on two appropriately timed specimens where both tests are done in =-the same laboratory at the same time, --Test developed and characteristics determined by ARUP --Laborstories. See Compliance Statement A: arupleb.com/Cs HEP. C Ab. Non- Non-Reactive TWP | 08/3e/2017 © Reactive itp C Ab. ($/€0 RATIO) -—~—~C~S~SaSt«~<S SB es ns |e Ce/3e/2e17 (38) Performed by: ARUP 596 Chipeta Way Salt Lake City, UT 84168 Hepatitis B Result Interpretation (for reference use only) Marker LI/EA* Acute Past Chronic HEY ; Vace. SOS RENEE ON 8 ER TAN HE EO OeS ERD RETR NE HK EC ESTER EEE TER HEHe eereeee HBsAg + + - + - HBeAg + + - +/- “ HEP.B.CORE AB, IgM - + - - - HEP,B.CORE AB. - + + + . HBeAb - - +/- +/- - HBsaAb . . +/~ - + *Late Incubation/Early Acute NOTE: In remote past infection, H8sAb level may be Negative or BioReference Laboratories, Inc. James Weiaberger M.D. Page 3 of 4 481 Edward H. Ross Dr | Elmwood Park, N2 07407 | aay Laboratory Director printed 9/19/2017 11:48 EFTA00299762

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BioReference LABORATORIES an OP KO Health Comseny ORSHER, STUART C3076 - STUART ORSHER, M.D. 9 EAST 79TH ST, INEW YORK, NY 18021 ect #: (C3678) CLINICAL REPORT Yon-Reactave in some patients. EPSTEIN, JEFFREY DOB: 21/20/1953 Age: 64 y Sex: M U/FL: Bed: Rm: Address:9 EAST 71ST STREET, NEW YORK, NY 10822 PRELIMINARY Specimen ID: 164659439 Date OF Report: 69/19/2017 85:29 Date Collected: 69/15/2017 63:57 Date Received: 69/15/2017 23:26 FOLIC ACID 7.77 “95.38 ng/mL | ™NP 08/36/2017 Folic Acid Range Units (ng/ml) Normal >5.38 Borderline deficient 3.38-5.38 Deficient @.35-3.37 Excessive >24.08 VITAMIN B12 “389 241-911 pg/ml TNP 08/30/2017" 250H, VITAMIN D 31.5 LO 328-180.9 ng/ml TWP | 08/30/2017 VITAMIN 0,25-OH TEST INFORMATION Range (ng/ml) Suggested Interpretation <26.8 Deficient 26.6-31.9 Insufficient 32,.0-100.0 Sufficient >146.8 Possible Adverse Effects ViT D1, 2SDIHYDROXY 52.0 19.9-79.3 pa/mi 08/30/2617 PTH(3), INTACT 13.8-85.8 pe/mL 08/30/2617 “PNEUMO Ab TYPE 1 (58) “TO FOLLO eee : "68/30/2017 PNEUMO Ab TYPE 3 (58) TO FOLLOW 08/30/2017 SPNEUMO Ab TYPE 4 (58) TO FOLLOW ~ ~ 08/38) 2¢17 ~~ PNEUMO Ab TYPE 8 (58) TO FOLLOW 08/36/2027 “PNEUMO Ab TYPE 9 (SN) (58) | TO FOLLOW ~ ~ 88/30/2017 PNEUMO Ab TYPE 12 (12F) (58) TO FOLLOW 08/30/2027 “PNEUMO A TYPE 14 (58) SST FOLLOW ee 68/30/2017 PNEUMO Ab TYPE 19 (19F) (58) TO FOLLOW 08/30/2017 {PNEUMO Ab TYPE 23 (23F) (58) TO FOLLOW 08/30/2017 PNEUMO Ab TYPE 265 (6B) (58) TO FOLLOW 28/30/2817 “PNEUMO- Ab TYPE 5 (58) “"FO FOLLOW oo | 0873072017 PNEUMO Ab TYPE S1 (7F) (58) TO FOLLOW 68/30/2017 |PNEUMO' Ab TVPE 56° (icy (58) TO FOLLOW “68/30/2817 PNEUMO Ab TYPE 68 (9V) (58) TO FOLLOW 8/30/2017 B.Henselae IgG Ab (3) ~~ SS TO FOLLOW “| 6873673817 — B.Henselae Igh Ab (3) TO FOLLOW €2/38/2817 NOTE: Specimen submitted is LIPEMIC. This may cause inaccurate results. Please resubmit a fasting specimen at your earliest convenience. Page 4 of 4 Printed @9/19/2017 11:48 BioReference Laboratories, Inc. 481 Edward H. Ross Dr | Elmwood Park, n3 67407 | [i James Weisberger M.D. Laboratory Director EFTA00299763

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BioReference CABORATORIES an OPKO Heath Company ORSHER, STUART 9 EAST 79TH ST, NEW YORK, NY 10021 Acct #: (C3@7@) °- €387@ = STUART ORSHER, M.D. | T2 UPTAKE (T3U) ‘THYROXINE; FREE (FTA) ‘FREE T4 INDEX 'T3 (THYRONINE), TOTAL HEP. A Ab., IgM CLINICAL REPORT EPSTEIN, JEFFREY U/FL: Rm: Patient ID: Address:9 EAST 71ST STREET, NEW YORK, NY 10821 Bed: DOB: 21/28/1953 Age: 6a Y Sex: m| @.88-1.73 2.3 1.5-3.8 a7 74-186 Non- Non-Reactive Reactive NOTE: Hep A Ab, IgM is positive or reactive during the acute phase. Hep A Ab/Total is positive or reactive during the recovery phase or is indicative of a past infection. HEP. A Ab., TOTAL HEP. B CORE Ab. IGG HEP. B SURF. AG HEP. BE AB, HEP. BE AG, “TESTOSTERONE, TOT.,S. Reactive * Non-Reactive Non- Non-Reactive Reactive —— tive * Non-Reactive® Non- Non-Reactive Reactive Negative ‘Negative Negative Negative ar 153.8-748.0 NOTE: Patients receiving the drug Nandrolone cannot be tested for TESTOSTERONE, total using the EIA method (test code 6379-8) due to a strong interference from the drug. Clinicians are asked to request Testosterone, Total by LC/MS/MS (test code 3451-6) for these patients. SEX HORM. BINO.GLOB. ‘FREE TESTOSTERONE iH , cK 8 \ AB G/M (38) B. quintane ab, Igh 14 18-57 52.04 ~ 36.66-156. 00 3.8 1.7-8.6 : ~ 42 ~ a 1. + 286 39-308 “SEE BELOW © ee «1:16 INTERPRETIVE INFORMATION: Bartonella quintana Ab, IgM Less then 1:16 1:16 oF greater Negative-No significant level of Bartonella quintana IgM antibody detected. Positive-Presence of IgM antibody to Bartonella quintana detected, Suggestive of current or recent infection. ~The presence of IgM antibodies suggests recent infection. Low BioReference Laboratories, inc. 481 Edward H. Ross Dr | Elmwood Park, »J 07407 | is PRELIMINARY Specimen ID: 164659439 Date OF Report: e9/19/2017 85:29 Date Collected: 09/15/2017 98:57 | Date Received: 29/15/2617 23:06 | | North Amertco Eastern Time 5 8/30/2617 08/38/2017 08/36/2017 ~~ ng/a | 08 /8073807"~ TP | 08/30/2617 TNE | 88/30/2017 ~~ The) 68738 / 2617 TNP 02/30/2017 TNP 88 /36726i7~ TuP 08/30/2617 “Tig/dt : Tie ~~ | €8/30/2617_ nmol/L pe/m rn | mIU/mL ~mTU/al rs U/L 346 HI 8/30/2017 a “SEE BELOW | 8/3/2017 — James Welsberger M.D. Page 2 of 4 Laboratory Director printed @9/19/2017 11:48 EFTA00299764